Masek lab
Research at Charles UniversityWe are a newly established lab focused on solving medically relevant basic biological questions.
We strive to gain a better mechanistic insight into the processes co-regulated by direct protein-protein interaction between components of Notch and Wnt pathways and Non-canonical Notch-ligand mediated signaling in development, homeostasis and disease.
Developmental and cellular biology, mouse models. Medically relevant basic research focusing on Non-canonical Notch signaling and WNT/NOTCH crosstalks in development, homeostasis and disease. PRIMUS funded project.
Team leader & members
- Dr. Jan Mašek
- Daniel Oliveira (postdoc)
- Anna Maria Frontino (PhD student)
- Fabio Turetti (PhD student)
- Hana Hajšmanová (undergraduate)
Selected publications
- CHODELKOVA O, MASEK J, KORINEK V, KOZMIK Z & MACHON O (2018) Tcf7L2 is essential
for neurogenesis in the developing mouse neocortex. Neural Dev. 13: 8 (Scopus citations: 3) - MAŠEK J & ANDERSSON ER (2017) The developmental biology of genetic Notch disorders. Development 144: 1743–1763
- MAŠEK J, MACHOŇ O, KOŘÍNEK V, TAKETO MM & KOZMIK Z (2016) Tcf7l1 protects the anterior neural fold from adopting the neural crest fate. Development 143: 2206–2216
Contact
Charles University
Faculty of Science
Mgr. Jan Mašek, Ph.D.
E-mail: jan.masek@natur.cuni.cz
More information
We have an interest for motivated post graduate students interesting in cooperation.
PhD, master students and postdoc applicants, please send your CV, motivation and a reference letter.
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